Nucci M, Portugal R, Pulcheri W, Spector N, Ferreira S B, de Castro M B, Noe R, de Oliveira H P
Hematology Service, University Hospital, Federal University of Rio de Janeiro Medical School, Brazil.
Clin Infect Dis. 1995 Sep;21(3):675-7. doi: 10.1093/clinids/21.3.675.
We retrospectively studied 343 consecutive patients treated between 1979 and 1992. Ninety patients whose stool was not examined were excluded. Fifty-three patients with strongyloidiasis were compared with 200 controls with regard to outcomes and the following characteristics: age, sex, underlying disease, use of corticosteroids, abdominal pain, diarrhea, fever, pulmonary symptoms, and eosinophilia. Patients with strongyloidiasis more commonly had eosinophilia (P = .01) and fever (P = .03). There was a single but fatal case of the disseminated disease syndrome (1.9% of patients with strongyloidiasis). In multiple logistic regression analysis, the factors predictive for strongyloidiasis were schistosomiasis (odds ratio [OR], 6.58), ascariasis (OR, 2.78), and the use of steroids (OR, 2.29). Strongyloidiasis was highly prevalent among patients with hematologic malignancies in Brazil. Occurrence of the disseminated disease syndrome seems to be unusual.
我们回顾性研究了1979年至1992年间连续治疗的343例患者。排除了90例未进行粪便检查的患者。将53例类圆线虫病患者与200例对照者在结局以及以下特征方面进行比较：年龄、性别、基础疾病、皮质类固醇的使用、腹痛、腹泻、发热、肺部症状和嗜酸性粒细胞增多。类圆线虫病患者更常见嗜酸性粒细胞增多（P = 0.01）和发热（P = 0.03）。有1例播散性疾病综合征病例，但为致命病例（占类圆线虫病患者的1.9%）。在多因素逻辑回归分析中，类圆线虫病的预测因素为血吸虫病（比值比[OR]，6.58）、蛔虫病（OR，2.78）和类固醇使用（OR，2.29）。在巴西，类圆线虫病在血液系统恶性肿瘤患者中高度流行。播散性疾病综合征的发生似乎不常见。
