Scagliusi P
Minerva Med. 1978 Dec 29;69(63):4369-79.
The results of 835 studies of LE cells carried out over 8 years in 563 clinical cases of various nature are reported. The LE phenomenon--i.e. LE cells, LE globs and rosettes--was encountered exclusively in patients with LES, whereas tart-cells, nucleophagocytosis A and nucleophagocytosis B, although present in initial LES, and particularly in regressing LES, were very frequent in many other conditions. It is therefore held that true LE phenomenon is pathognomonic of LES since so-called AR with LE cells can be considered a clinical variant of LES, whereas lupoid hepatitis remains a vague, uncertain syndrome.
报告了在563例各种性质的临床病例中进行的为期8年的835项LE细胞研究结果。LE现象——即LE细胞、LE小球和玫瑰花结——仅在系统性红斑狼疮(LES)患者中出现,而棘细胞、噬核现象A和噬核现象B虽然在早期LES中存在,特别是在病情缓解的LES中存在,但在许多其他病症中也很常见。因此,人们认为真正的LE现象是LES的特征性表现,因为所谓的伴有LE细胞的自身免疫性疾病(AR)可被视为LES的一种临床变异,而类狼疮性肝炎仍然是一种模糊、不确定的综合征。