Apffelstaedt J P, Zhang P J, Driscoll D L, Karakousis C P
State University of New York, Buffalo 14209, USA.
Surg Oncol. 1995 Aug;4(4):217-22. doi: 10.1016/s0960-7404(10)80038-6.
Fifty-three hemipelvectomies were performed for primary or recurrent soft tissue sarcomas with fixation to the pelvis or peripelvic tissues. Resection was carried out in the absence of distant metastases in 70% of the cases. The hemipelvectomy was posterior in 66%, anterior in 6% and internal in 28%. Post-operative complications included wound edge necrosis in 19% and infection in 43% of cases. The mortality rate was 5.7%. Margins were macroscopically clear in 76% and marginal in 24% of cases. Tumours were high grade in 92%; their mean diameter was 16.5 cm. Local recurrence occurred in 19% and distant recurrence in 66% of patients. Overall survival was 39% at 2 years and 10% at 5 years. Pelvic soft tissue sarcomas have a poor prognosis. However, in the absence of other effective therapy, hemipelvectomy provides local control with acceptable morbidity in the majority of patients, with a small percentage (10%) surviving 5 years or longer.
对53例因原发性或复发性软组织肉瘤固定于骨盆或骨盆周围组织而进行了半骨盆切除术。70%的病例在无远处转移的情况下进行了切除。半骨盆切除术66%为后路，6%为前路，28%为内侧入路。术后并发症包括19%的病例出现伤口边缘坏死，43%的病例出现感染。死亡率为5.7%。76%的病例切缘肉眼可见为阴性，24%为边缘阳性。92%的肿瘤为高级别；平均直径为16.5 cm。19%的患者出现局部复发，66%出现远处复发。2年总生存率为39%，5年为10%。骨盆软组织肉瘤预后较差。然而，在没有其他有效治疗方法的情况下，半骨盆切除术能在大多数患者中实现局部控制，且发病率可接受，有一小部分（10%）患者存活5年或更长时间。
