Mitchell R A, Berger A J
Int Anesthesiol Clin. 1977 Summer;15(2):59-79. doi: 10.1097/00004311-197715020-00003.
During the last decade, we have seen our knowledge of the neural regulation of respiration progress from the concept of "respiratory centers" to that of densely packed groups of respiratory neurons located within specific medullary nuclei. By careful neurophysiological and histological studies employing intra- and extracellular recording, the sequence of processing of afferent information through these nuclei and the axonal projections from respiratory neurons have been determined. However, the site and the mechanism of respiratory rhythm generation remain unknown.
在过去十年间，我们对呼吸神经调节的认识已从“呼吸中枢”的概念发展到位于特定延髓核内的密集排列的呼吸神经元群的概念。通过运用细胞内和细胞外记录的细致神经生理学和组织学研究，已经确定了传入信息通过这些核的处理顺序以及呼吸神经元的轴突投射。然而，呼吸节律产生的部位和机制仍然未知。
