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早产儿与药理学。

Premature babies and pharmacology.

作者信息

Hamilton J

出版信息

CMAJ. 1995 Dec 15;153(12):1745-8.

Abstract

In his research on the action of various drugs in newborns, Dr. Jacob Aranda of the Centre for Perinatal and Developmental Pharmacology Research in Montreal draws upon his expertise in both neonatology and pharmacology. His work has led to the acceptance of caffeine as a standard treatment of apnea in premature infants, and his current studies of ibuprofen as a possible treatment of cerebral intraventricular hemorrhage, a serious problem in some premature babies, have yielded promising results. Other areas being tackled by Aranda and his colleagues include pain control for newborns and the elusive pathology of sudden infant death syndrome. By shedding more light on neonatal development and the principles of drug action in newborns, these research projects will help to improve the odds for many babies who suffer the setback of being born too soon.

摘要

蒙特利尔围产期与发育药理学研究中心的雅各布·阿兰达博士在研究各种药物对新生儿的作用时,借鉴了他在新生儿学和药理学方面的专业知识。他的工作使咖啡因被接受为早产儿呼吸暂停的标准治疗方法,而且他目前对布洛芬作为治疗脑室内出血(一些早产儿面临的严重问题)的可能性研究已取得了有希望的结果。阿兰达及其同事正在研究的其他领域包括新生儿的疼痛控制以及难以捉摸的婴儿猝死综合征病理学。通过更深入地了解新生儿发育和新生儿药物作用原理,这些研究项目将有助于提高许多早产受挫婴儿的生存几率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9137/1488195/9c71ca972afa/cmaj00084-0052-a.jpg

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