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绿茶浸出液对小鼠肺癌细胞体外侵袭和体内转移的抑制作用。

Inhibitory effects of green tea infusion on in vitro invasion and in vivo metastasis of mouse lung carcinoma cells.

作者信息

Sazuka M, Murakami S, Isemura M, Satoh K, Nukiwa T

机构信息

School of Food and Nutritional Sciences, University of Shizuoka, Japan.

出版信息

Cancer Lett. 1995 Nov 27;98(1):27-31.

PMID:8529202
Abstract

The peroral administration of green tea infusion reduced the number of lung colonies of mouse Lewis lung carcinoma cells in a spontaneous metastasis system. The experiments with artificially reconstituted basement membrane suggested that this reduction could be understood by the inhibitory effects of the green tea infusion and its constituent catechins on the penetration of the cells through the basement membrane.

摘要

在自发转移系统中，经口给予绿茶浸出液可减少小鼠Lewis肺癌细胞的肺转移瘤数量。用人造重组基底膜进行的实验表明，这种减少可归因于绿茶浸出液及其成分儿茶素对细胞穿透基底膜的抑制作用。

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