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Tumor lysis syndrome following single-dose mitoxantrone.

作者信息

Benekli M, Savaş M C, Güllü I H, Kadayifçi A, Akpek G, Kars A, Güler N, Kansu E, Tekuzman G, Firat D

机构信息

Department of Internal Medicine, Hacettepe University, Faculty of Medicine, Ankara, Turkey.

出版信息

Chemotherapy. 1995 Nov-Dec;41(6):470-2. doi: 10.1159/000239384.

Abstract

We report here a 16-year-old boy with pre-B-type acute lymphoblastic leukemia who developed acute tumor lysis syndrome (TLS) following 12 h mitoxantrone infusion. TLS is a distinct clinical entity which has been recognized most frequently with aggressive combination chemotherapy of rapidly proliferating hematologic neoplasms. There have been a few reports of single-agent-induced tumor lysis, but to our knowledge, this is the first case reported with mitoxantrone alone.

摘要

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