Ross H E
Social Evaluation and Research Department, Addiction Research Foundation, Toronto, Ontario, Canada.
Drug Alcohol Depend. 1995 Aug;39(2):111-28. doi: 10.1016/0376-8716(95)01150-w.
The lifetime prevalence of DSM-III-R alcohol abuse and alcohol dependence and associated patterns of psychiatric comorbidity in the Ontario population aged 15-64 years are estimated from a survey of a representative household sample using the University of Michigan Composite International Diagnostic Interview (UM-CIDI). More than half (55%) of all individuals with an alcohol disorder have a lifetime comorbid disorder and comorbidity is more common in women than in men with an alcohol disorder. The odds of having other drug disorders and antisocial personality disorder are very high in individuals with an alcohol disorder compared to those without. Alcohol dependents, but not alcohol abusers, have significantly increased odds of mood and anxiety disorders compared to individuals without an alcohol disorder. Sociodemographic risk profiles, alcohol use patterns and course differ for alcohol abusers/dependents with and without a comorbid disorder. Primary anxiety and drug disorders are risk factors for subsequent alcohol disorders.
利用密歇根大学综合国际诊断访谈(UM-CIDI),通过对具有代表性的家庭样本进行调查,估算了安大略省15至64岁人群中DSM-III-R酒精滥用、酒精依赖的终生患病率以及相关的精神共病模式。所有患有酒精障碍的个体中,超过一半(55%)患有终生共病障碍,并且在患有酒精障碍的女性中,共病比男性更为常见。与没有酒精障碍的个体相比,患有酒精障碍的个体出现其他药物障碍和反社会人格障碍的几率非常高。与没有酒精障碍的个体相比,酒精依赖者(而非酒精滥用者)出现情绪和焦虑障碍的几率显著增加。有共病障碍和没有共病障碍的酒精滥用者/依赖者在社会人口统计学风险概况、饮酒模式和病程方面存在差异。原发性焦虑和药物障碍是随后发生酒精障碍的风险因素。