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压力性尿失禁女性患者阴道膀胱筋膜中雌激素受体的免疫组化定位——初步报告

[Immunohistochemical localization of estrogen receptors in vesicovaginal fascia among female patients with stress incontinence--preliminary report].

作者信息

Rechberger T, Miturski R

机构信息

II Kliniki Ginekologii Operacyjnej AM, Lublinie.

出版信息

Ginekol Pol. 1995 Apr;66(4):231-6.

PMID:8529941
Abstract

Using monoclonal antibody assay technique 29 kD domain of estrogen receptor was found and partially quantitated by means of histological score in fibroblasts from vesico-vaginal fascia obtained during surgical procedure in incontinent women. This is an important proof that estrogen supplementation therapy is a reasonable approach in women affected by urinary stress incontinence.

摘要

采用单克隆抗体检测技术,在手术过程中从尿失禁女性的膀胱阴道筋膜获取的成纤维细胞中发现了雌激素受体的29 kD结构域,并通过组织学评分进行了部分定量。这是一个重要证据,表明雌激素补充疗法对于受压力性尿失禁影响的女性是一种合理的治疗方法。

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