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Assignment of DAP1 and DAPK--genes that positively mediate programmed cell death triggered by IFN-gamma--to chromosome regions 5p12.2 and 9q34.1, respectively.

作者信息

Feinstein E, Druck T, Kastury K, Berissi H, Goodart S A, Overhauser J, Kimchi A, Huebner K

机构信息

Department of Molecular Genetics and Virology, Weizmann Institute of Science, Rehovot, Israel.

出版信息

Genomics. 1995 Sep 1;29(1):305-7. doi: 10.1006/geno.1995.1255.

DOI:10.1006/geno.1995.1255
PMID:8530096
Abstract
摘要

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1
Assignment of DAP1 and DAPK--genes that positively mediate programmed cell death triggered by IFN-gamma--to chromosome regions 5p12.2 and 9q34.1, respectively.将DAP1和DAPK（分别为正向介导由γ-干扰素触发的程序性细胞死亡的基因）分别定位于染色体区域5p12.2和9q34.1。
Genomics. 1995 Sep 1;29(1):305-7. doi: 10.1006/geno.1995.1255.
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Retinoblastoma protein inhibits IFN-gamma induced apoptosis.视网膜母细胞瘤蛋白抑制γ干扰素诱导的细胞凋亡。
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Death associated proteins (DAPs): from gene identification to the analysis of their apoptotic and tumor suppressive functions.死亡相关蛋白（DAPs）：从基因鉴定到其凋亡和肿瘤抑制功能分析
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mRNA expression profiles of methylated APAF-1 and DAPK-1 tumor suppressor genes uncover clear cell renal cell carcinomas with aggressive phenotype.甲基化的凋亡蛋白酶激活因子-1（APAF-1）和死亡相关蛋白激酶-1（DAPK-1）肿瘤抑制基因的信使核糖核酸（mRNA）表达谱揭示了具有侵袭性表型的透明细胞肾细胞癌。
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Radiation-induced cell death is independent of the apoptotic signals mediated by death-associated protein kinase in human cervical squamous cell carcinoma cells.辐射诱导的细胞死亡独立于人类宫颈鳞状细胞癌细胞中由死亡相关蛋白激酶介导的凋亡信号。
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