Kaplan R F, Cohen R A, Rosengart A, Elsner A E, Hedges T R, Caplan L R
Department of Neurology, Tufts University School of Medicine, Boston, MA, USA.
J Neurol Neurosurg Psychiatry. 1995 Nov;59(5):534-6. doi: 10.1136/jnnp.59.5.534.
The temporal variables of extinction in two patients with right hemispheric stroke and two normal controls were studied using a scanning laser ophthalmoscope (SLO). This instrument enabled eye movements to be controlled for by projecting time controlled stimuli directly on to the retina. Both patients had recovered from their stroke (four months and five years) and seemed clinically normal. At 50 ms, patient 1 extinguished one of two stimuli on seven of 40 double simultaneous stimulation (DSS) trials (five left, two right) and patient 2 extinguished the left stimulus on every DSS trial. At 100 ms, patient 1 performed almost perfectly, whereas patient 2 extinguished on 30% of the DSS trials (10 left, two right). At 200 ms, patient 2 performed perfectly. Neither of the controls showed extinction to DSS at any presentation time. Thus detecting DSS was time dependent in the patients but not the normal subjects. These data support the theory that recovery from neglect after right hemispheric damage may be mediated by the left hemisphere.
使用扫描激光检眼镜（SLO）研究了两名右半球中风患者和两名正常对照者的消退时间变量。该仪器通过将时间控制的刺激直接投射到视网膜上来控制眼球运动。两名患者均已从中风康复（分别为四个月和五年），临床症状看似正常。在50毫秒时，患者1在40次双眼同时刺激（DSS）试验中的7次试验中消去了两个刺激中的一个（5次消去左侧刺激，2次消去右侧刺激），患者2在每次DSS试验中均消去左侧刺激。在100毫秒时，患者1表现几乎完美，而患者2在30%的DSS试验中出现消去现象（10次消去左侧刺激，2次消去右侧刺激）。在200毫秒时，患者2表现完美。两名对照者在任何呈现时间均未出现对DSS的消去现象。因此，患者中检测到DSS存在时间依赖性，而正常受试者则不存在。这些数据支持了右半球损伤后从疏忽中恢复可能由左半球介导的理论。
