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儿童因赛庚啶引发的中枢性抗胆碱能综合征:一例报告

Cyproheptadine-induced central anticholinergic syndrome in a child: a case report.

作者信息

Blaustein B S, Gaeta T J, Balentine J R, Gindi M

机构信息

Department of Emergency Medicine, St. Barnabas Hospital, Bronx, New York 10457, USA.

出版信息

Pediatr Emerg Care. 1995 Aug;11(4):235-7. doi: 10.1097/00006565-199508000-00012.

DOI:10.1097/00006565-199508000-00012
PMID:8532571
Abstract

A 16-year-old female patient presented to our emergency department with anticholinergic psychosis after an ingestion of cyproheptadine. The central anticholinergic syndrome occurs frequently but often goes unrecognized because many patients do not fit into a well defined clinical pattern. The diagnosis depends on the suspicion and recognition of the psychiatric manifestations, including agitation, confusion, and hallucinations. A high index of suspicion is necessary in children in particular, since central effects seem to predominate in many anticholinergic overdoses.

摘要

一名16岁女性患者在服用赛庚啶后因抗胆碱能性精神病被送至我院急诊科。中枢抗胆碱能综合征经常发生,但往往未被识别,因为许多患者不符合明确的临床模式。诊断取决于对精神症状的怀疑和识别,包括躁动、意识模糊和幻觉。特别是对于儿童,必须保持高度怀疑,因为在许多抗胆碱能药物过量中毒中,中枢效应似乎占主导。

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