Wade T P, Virgo K S, Johnson F E
Department of Surgery, John Cochran VA Medical Center, St. Louis, Missouri, USA.
Pancreas. 1995 Nov;11(4):341-4.
Although cancers of the pancreatic body and tail are often advanced at the time of diagnosis, resection of localized tumors can result in long-term survival. A search of the computerized records of the U.S. Department of Veterans Affairs (DVA) revealed 29 distal pancreatectomies performed for pancreatic cancer from 1987 to 1991. Operative complications and survival data were available on all patients, and pathologic and staging information were retrieved on 21 patients, seven of whom had cancers other than pancreatic adenocarcinoma. Although 30-day mortality was high after distal pancreatectomy (21%), mean survival exceeded 1 year for patients with localized pancreatic adenocarcinoma and for those with histologies other than pancreatic cancer. Surgical resection should be offered to patients with lesions of the pancreatic body and tail when metastases are not demonstrated; survival will likely be prolonged when nodal or systemic metastases are absent. These recent DVA results from a wide variety of surgeons, hospital sizes, and university affiliations may more closely reflect the national experience with this operation in patients with cancer than do single institutional reports.
尽管胰体尾癌在诊断时通常已属晚期，但对局限性肿瘤进行切除可实现长期生存。检索美国退伍军人事务部（DVA）的计算机记录发现，1987年至1991年间有29例因胰腺癌行胰体尾切除术。所有患者均有手术并发症及生存数据，21例患者获取了病理及分期信息，其中7例为非胰腺腺癌。尽管胰体尾切除术后30天死亡率较高（21%），但局限性胰腺腺癌患者及非胰腺癌组织学类型患者的平均生存期均超过1年。当未发现转移时，应对胰体尾病变患者进行手术切除；若无区域或全身转移，生存期可能延长。退伍军人事务部近期来自各种外科医生、不同规模医院及不同大学附属医院的结果，可能比单一机构报告更能准确反映全国范围内该手术治疗癌症患者的实际情况。
