Shankar P M
Department of Electrical and Computer Engineering, Drexel University, Philadelphia, PA 19104, USA.
Phys Med Biol. 1995 Oct;40(10):1633-49. doi: 10.1088/0031-9155/40/10/006.
A model for the backscattered ultrasound echo from tissues is presented. The model takes into account the fact that the range cell being insonified may contain only a few scatterers and the number may not be large enough to justify the use of a Gaussian model which results in Rayleight statistics for the echo. Furthermore, the model also considers the case where the echogenicity of the scatterers in the range cell may not be uniform, the lack of uniformity resulting from variations in scattering cross-sections produced by the chemical as well as biochemical changes brought on by the presence of disease, growth of benign or malignant tumours, etc. The model is developed from the fundamental principles of scattering using the results available in radar. This new model results in a two-parameter distribution, namely the K distribution for the echo, thereby making it possible to gain information on the number as well as scattering cross-sections of the scatterers in the range cell. The model is extended to include the effects due to the presence of scatterers having some regular or periodic orientation in the range cell, resulting in the so-called generalized K distribution which approximates to Rayleight, Rician, or Gaussian under various limiting cases. Results of computer simulations and experiments on tissue-mimicking phantoms are also provided, which strongly suggest that this new model offers potential for tissue characterization.
提出了一种用于组织后向散射超声回波的模型。该模型考虑到被声照射的距离单元可能仅包含少数散射体,且数量可能不足以证明使用导致回波呈瑞利统计的高斯模型是合理的。此外,该模型还考虑了距离单元中散射体的回声性可能不均匀的情况,这种不均匀性是由疾病、良性或恶性肿瘤生长等导致的化学以及生化变化所产生的散射截面变化引起的。该模型是根据散射的基本原理,利用雷达领域的现有成果开发的。这个新模型产生了一种双参数分布,即回波的K分布,从而有可能获取距离单元中散射体数量以及散射截面的信息。该模型被扩展以包括由于距离单元中存在具有某些规则或周期性取向的散射体而产生的影响,从而产生了所谓的广义K分布,在各种极限情况下,该分布近似于瑞利分布、莱斯分布或高斯分布。还提供了对仿组织体模进行计算机模拟和实验的结果,这些结果有力地表明,这个新模型具有组织表征的潜力。