Pallotta S, Gilardi M C, Bettinardi V, Rizzo G, Landoni C, Striano G, Masi R, Fazio F
Nuclear Medicine Department, Ospedale Careggi, Firenze, Italy.
Phys Med Biol. 1995 Oct;40(10):1695-708. doi: 10.1088/0031-9155/40/10/010.
The aim of this work is to assess the accuracy of a surface matching registration (SMR) technique for the correlation of cardiac studies in positron emission tomography (PET). Registration parameters were estimated by matching corresponding body surfaces, extracted from transmission studies, aligned to the PET emission images to be correlated. The accuracy of the SMR technique in this specific application was assessed by computer simulations, phantom experiments and on clinical PET data. Registration accuracy was evaluated in relation to the body surfaces (external, internal and the combination of the two) used by the SMR method. Better results were found when matching shaped and irregular surfaces such as internal lung contours. The robustness of the method was verified for different counting statistics recorded in transmission images. A clinical validation of the SMR method was performed on fluorine-18-deoxyglucose PET cardiac studies.
这项工作的目的是评估用于正电子发射断层扫描（PET）心脏研究相关性的表面匹配配准（SMR）技术的准确性。通过匹配从透射研究中提取的相应身体表面来估计配准参数，将这些表面与要进行相关性分析的PET发射图像对齐。通过计算机模拟、体模实验以及临床PET数据评估了该SMR技术在这一特定应用中的准确性。根据SMR方法所使用的身体表面（外部、内部以及两者的组合）评估配准准确性。当匹配诸如肺内轮廓等形状不规则的表面时，获得了更好的结果。针对透射图像中记录的不同计数统计情况验证了该方法的稳健性。对氟-18-脱氧葡萄糖PET心脏研究进行了SMR方法的临床验证。
