Filatova E G, Solov'eva A D, Kanavets E V, Rogovina E G
Zh Nevrol Psikhiatr Im S S Korsakova. 1995;95(4):14-20.
Peripheral vegetative nervous system state was estimated in 61 patients with constitutional acquired hypothalamic insufficiency by using non-invasive methods. Control group consisted of 10 healthy individuals. Cardiovascular tests application led to the evaluation of subclinical parasympathetic vegetative insufficiency. In was more prominent in patients with early neuroendocrine disorders debut as well as in those with more protracted disease durations. The authors suggest that these findings testify the constitutional acquired character of disturbances. Besides it was also found the conductivity velocity fall in sudomotor preganglionic fibers in arms and legs and the prevalence of such disorders in patients with expressed dysraphic status. The last observation may testify the defect in laying of these peripheral vegetative fibers. The study carried out permits to suppose that subclinical peripheral insufficiency occur to be one of the factors evoking rise either of permanent (tachycardia, arterial pressure elevation, hyperhidrosis) or of paroxysmal vegetative disturbances (panic attacks, migraine) in patients with hypothalamic insufficiency.
采用非侵入性方法对61例体质性获得性下丘脑功能不全患者的外周自主神经系统状态进行了评估。对照组由10名健康个体组成。应用心血管测试对亚临床副交感神经自主功能不全进行了评估。在神经内分泌紊乱早期发病的患者以及病程较长的患者中更为明显。作者认为这些发现证实了紊乱的体质性获得性特征。此外，还发现手臂和腿部汗腺节前纤维的传导速度下降，并且在有明显脊柱裂状态的患者中这种紊乱更为普遍。最后这一观察结果可能证实了这些外周自主神经纤维发育的缺陷。所进行的研究使人们推测，亚临床外周功能不全是下丘脑功能不全患者出现持续性（心动过速、血压升高、多汗）或阵发性自主神经紊乱（惊恐发作、偏头痛）的诱发因素之一。
