Mizutani K, Ono Y, Kato N, Takeda A, Yamada S, Kinukawa T, Hattori R, Sahashi M, Matsuura O, Takeuchi N
Department of Urology, Komaki Shimin Hospital.
Hinyokika Kiyo. 1995 Nov;41(11):867-71.
Between September, 1987 and September, 1993, a total of 44 consecutive patients had undergone radical retropubic prostatectomy and pelvic lymphadenectomy for the treatment of prostate cancer. The patients were between 56 and 77 years (mean, 68 years). Eleven patients had clinical state A2 disease, 21 had stage B disease, and 12 had stage C disease. Fourteen of the 44 patients (32%) had positive lymph node metastases. The 5-year survival rate for patients with pT1, pT2 and pT3 was 100%, 71% and 87%, respectively. It was 77% in patients with positive node disease and 90% in patients with negative node disease. The 5-year disease-free survival rate for patients with pT1, pT2 and pT3 was 82%, and 78%, respectively. It was 54% in patients with positive node disease and 88% in patients with negative node disease. In 14 positive node patients, metastases were located in obturater nodes in 8 patients (57%), hypogastric nodes, in 6 patients (43%), external iliac nodes in 6 patients (43%), common iliac nodes in 4 patients (29%) and presacral nodes in 2 patients (14%). We confirmed that radical retropubic prostatectomy is effective treatment for locally confined prostate cancer and removal of obturater, hypogastric lymph nodes and the internal chain of external iliac lymph nodes is important in detecting metastases.
1987年9月至1993年9月期间，共有44例连续患者接受了耻骨后根治性前列腺切除术及盆腔淋巴结清扫术以治疗前列腺癌。患者年龄在56至77岁之间（平均68岁）。11例患者为临床A2期疾病，21例为B期疾病，12例为C期疾病。44例患者中有14例（32%）有阳性淋巴结转移。pT1、pT2和pT3期患者的5年生存率分别为100%、71%和87%。淋巴结阳性患者为77%，淋巴结阴性患者为90%。pT1、pT2和pT3期患者的5年无病生存率分别为82%和78%。淋巴结阳性患者为54%，淋巴结阴性患者为88%。在14例淋巴结阳性患者中，转移位于闭孔淋巴结8例（57%），下腹下淋巴结6例（43%），髂外淋巴结6例（43%），髂总淋巴结4例（29%），骶前淋巴结2例（14%）。我们证实耻骨后根治性前列腺切除术是治疗局限性前列腺癌的有效方法，清扫闭孔、下腹下淋巴结及髂外淋巴结内链对于发现转移很重要。
