Hossain M M, Bakir M, Pugh R N, Sheekh-Hussen M, Bin Ishaq S A, Berg D B, Lindblad B S
Faculty of Medicine & Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Ann Trop Paediatr. 1995 Sep;15(3):227-35. doi: 10.1080/02724936.1995.11747777.
During 1992 and 1993, 309 children aged 1-22 months (mo) and their mothers visiting an immunization facility in Al Ain city, Abu Dhabi Emirate, United Arab Emirates, were studied to (1) define blood haemoglobin (Hb) levels; (2) estimate the prevalence of anaemia; (3) examine the role of iron deficiency in causing anaemia; (4) identify the correlates of anaemia prevalence; and (5) assess the acceptability to parents of an anaemia screening test for their young children. The levels of Hb in all subjects and the levels of serum ferritin in anaemic (Hb < 11 g/dl) children aged > or = 6 mo and in non-pregnant women with Hb < 11 g/dl were determined by a HemoCue Photometer and an enzyme immunoassay, respectively. Each woman was interviewed to obtain pertinent data. In children, anaemia was detected in 3% of those aged 1-2 mo (Hb < 9 g/dl), in 8% of those aged 3-5 mo (Hb < 10 g/dl), and in 25-39% of those aged > or = 6 mo (Hb < 11 g/dl). Of 19 children tested, ten (53%) were iron-depleted (serum ferritin < 12 micrograms/l). After multivariate adjustment, the only significant positive correlate of anaemia in children was older age (1-5 mo vs 6-22 mo; odds ratio [OR]: 9.51; 95% confidence interval [CI]: 3.92-23.08). Anaemia was detected in 14% of pregnant women (Hb < 11 g/dl) and 16% of non-pregnant women (Hb < 12 g/dl).(ABSTRACT TRUNCATED AT 250 WORDS)
1992年至1993年期间,对309名年龄在1至22个月的儿童及其母亲进行了研究,这些儿童和母亲前往阿拉伯联合酋长国阿布扎比酋长国艾因市的一个免疫接种机构,目的是:(1)确定血血红蛋白(Hb)水平;(2)估计贫血患病率;(3)检查缺铁在导致贫血中的作用;(4)确定贫血患病率的相关因素;(5)评估家长对其幼儿贫血筛查试验的可接受性。所有受试者的Hb水平以及年龄≥6个月的贫血儿童(Hb<11 g/dl)和Hb<11 g/dl的非孕妇的血清铁蛋白水平,分别通过HemoCue光度计和酶免疫测定法测定。对每位女性进行访谈以获取相关数据。在儿童中,1至2个月龄的儿童中有3%检测出贫血(Hb<9 g/dl),3至5个月龄的儿童中有8%检测出贫血(Hb<10 g/dl),年龄≥6个月的儿童中有25%至39%检测出贫血(Hb<11 g/dl)。在接受检测的19名儿童中,10名(53%)缺铁(血清铁蛋白<12微克/升)。经过多变量调整后,儿童贫血的唯一显著正相关因素是年龄较大(1至5个月与6至22个月相比;优势比[OR]:9.51;95%置信区间[CI]:3.92至23.08)。14%的孕妇(Hb<11 g/dl)和16%的非孕妇(Hb<12 g/dl)检测出贫血。(摘要截短于250字)