Clark C K, Lester G D, Vetro T, Rice B
Department of Large Animal Clinical Sciences, JMHSC, College of Veterinary Medicine, University of Florida, Gainesville 32610-0136, USA.
Aust Vet J. 1995 Jul;72(7):249-52. doi: 10.1111/j.1751-0813.1995.tb03537.x.
Bronchoalveolar lavage (BAL) was performed at weekly intervals in 10 Thoroughbred horses in race training (group 1) and in 4 rested horses (group 2) for 10 weeks. Lavages were continued on a weekly basis in 4 group 1 horses for an additional 9 weeks (group 3). Cytological analysis of samples included leukocyte counts, erythrocyte counts, differential leukocyte counts, and haemosiderophage score. The mean leukocyte concentration was significantly lower in group 1 (92.1 +/- 4.6 cells/microL) when compared with group 2 (133.5 +/- 8.2 cells/microL), P = 0.037. The differential leukocyte data were not significantly different between groups. There was a large amount of variability in the percentage of macrophages and lymphocytes in the differential counts over time with no obvious trends. The proportion of neutrophils demonstrated a tendency to decrease over time for both groups 1 and 2. Erythrocyte counts and haemosiderin scores were significantly higher in the exercising group than the rested horses. Neither exercise nor the technique itself evoked an inflammatory response in the BAL fluid.
对10匹处于赛马训练中的纯种马（第1组）和4匹休息的马（第2组）每周进行一次支气管肺泡灌洗（BAL），持续10周。对第1组中的4匹马再持续每周灌洗9周（第3组）。样本的细胞学分析包括白细胞计数、红细胞计数、白细胞分类计数和含铁血黄素巨噬细胞评分。与第2组（133.5±8.2个细胞/微升）相比，第1组的平均白细胞浓度显著更低（92.1±4.6个细胞/微升），P = 0.037。两组之间白细胞分类数据无显著差异。随着时间推移，分类计数中巨噬细胞和淋巴细胞的百分比存在大量变异性，无明显趋势。第1组和第2组中性粒细胞比例均呈现随时间下降的趋势。运动组的红细胞计数和含铁血黄素评分显著高于休息的马。运动和灌洗技术本身均未在BAL液中引发炎症反应。
