Wakai S, Ito N, Sueoka H, Kawamoto Y, Hayasaka H, Tsutsumi H, Chiba S
Department of Pediatrics, Sapporo Medical University School of Medicine, Japan.
Pediatr Neurol. 1995 Sep;13(2):137-41. doi: 10.1016/0887-8994(95)00140-b.
We report 5 pediatric patients (2 male, 3 female; age range: 4-8 years) with complex partial status epilepticus (CPSE). Four patients had previous illnesses and mild motor or mental retardation. In 2 patients, CPSE was induced by inappropriate management or selection of antiepileptic drugs. Clinical features varied and automatisms were observed in 3 patients. In 1 patient, decreased physical tone with syncope and impaired consciousness with amaurosis were observed. The episodes of CPSE were continuous in 3 patients and recurrent in 2 patients. In 4 patients, ictal electroencephalographic (EEG) findings, including video-EEG analyses of 3 patients, demonstrated persistent focal epileptic features. Intravenous diazepam abolished CPSE in 3 patients with brief periods of definite EEG localizations remaining. In 4 patients, seizure prognoses were favorable after appropriate treatments; in 1 patient, seizures were intractable even after antiepileptic drug administration.
我们报告了5例患有复杂部分性癫痫持续状态（CPSE）的儿科患者（2例男性，3例女性；年龄范围：4至8岁）。4例患者有既往病史且有轻度运动或智力发育迟缓。2例患者的CPSE是由抗癫痫药物管理不当或选择不当诱发的。临床特征各异，3例患者出现自动症。1例患者出现肌张力降低伴晕厥以及意识障碍伴黑矇。CPSE发作在3例患者中呈持续性，在2例患者中呈复发性。4例患者的发作期脑电图（EEG）结果，包括3例患者的视频脑电图分析，显示出持续性局灶性癫痫特征。静脉注射地西泮使3例患者的CPSE终止，但仍有短暂的明确脑电图定位。4例患者经适当治疗后癫痫预后良好；1例患者即使在使用抗癫痫药物后癫痫仍难以控制。
