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质体基因中GIY - YIG亚类的内含子编码开放阅读框。

Intron-encoded open reading frame of the GIY-YIG subclass in a plastid gene.

作者信息

Paquin B, O'Kelly C J, Lang B F

机构信息

Département de Biochimie, Université de Montréal, Canada.

出版信息

Curr Genet. 1995 Jun;28(1):97-9. doi: 10.1007/BF00311888.

DOI:10.1007/BF00311888
PMID:8536320
Abstract

Group-I introns, containing open reading frames (ORFs) that code for homing endonucleases, are widely distributed amongst eukaryotic organellar genomes. However, endonucleases of the GIY-YIG subclass have a restricted distribution in mitochondria and bacteriophages, and have never been observed in plastids. We have found the GIY-YIG motif in an intronic ORF within the previously published psbA gene sequence from Chlamydomonas reinhardtii chloroplasts. Based on phylogenetic analysis and an evaluation of amino-acid substitutions, this ORF is not closely related to any of the other GIY-YIG ORFs. These results suggest that GIY-YIG ORFs have a longer evolutionary history than previously assumed.

摘要

第一类内含子含有编码归巢内切核酸酶的开放阅读框（ORF），广泛分布于真核生物细胞器基因组中。然而，GIY-YIG亚类的内切核酸酶在线粒体和噬菌体中的分布有限，从未在质体中观察到。我们在莱茵衣藻叶绿体先前发表的psbA基因序列的一个内含子ORF中发现了GIY-YIG基序。基于系统发育分析和氨基酸替换评估，该ORF与其他任何GIY-YIG ORF均无密切关系。这些结果表明，GIY-YIG ORF的进化历史比先前假设的更长。

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A maturase-like coding sequence downstream of the OXI2 gene of yeast mitochondrial DNA is interrupted by two GC clusters and a putative end-of-messenger signal.酵母线粒体 DNA 的 OXI2 基因下游有一个与成熟酶相似的编码序列，该序列被两个 GC 簇和一个假定的信使 RNA 终止信号所中断。
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弯孢足孢菌线粒体基因组中的内含子GIY - YIG核酸内切酶基因：可移动性的证据
Nucleic Acids Res. 2000 Mar 15;28(6):1299-306. doi: 10.1093/nar/28.6.1299.
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