Dillon E, Renwick M
North Tees Hospital, Stockton on Tees, UK.
Clin Radiol. 1995 Dec;50(12):855-9. doi: 10.1016/s0009-9260(05)83107-1.
One hundred and twenty abdominal wall defects were notified to the Northern Region Fetal Abnormality Survey in the five years 1988 to 1992. Gastroschisis occurred in 56, exomphalos in 43, amnion rupture in 11, ectopia vesicae in seven and ectopia cordis in three. Ultrasound failed to identify gastroschisis in 14 and incorrectly diagnosed exomphalos in eight. There was no associated chromosome abnormality and the survival rate, excluding first trimester loss, was 87%. Ultrasound failed to identify exomphalos in ten and incorrectly diagnosed gastroschisis in two. Another structural abnormality was present in 40% and a chromosome anomaly in 28%. Excluding spontaneous first trimester loss, the survival rate was 34%. Delivery of babies away from the regional paediatric surgical centre did not adversely affect the outcome in gastroschisis or exomphalos although closure was delayed, on average, by 2 h. There was one survivor of 11 fetuses with amnion rupture sequence. Six of the seven babies with ectopia vesicae and two of the three with ectopia cordis survived.
在1988年至1992年的五年间，北方地区胎儿异常调查共收到120例腹壁缺损报告。其中腹裂56例，脐膨出43例，羊膜破裂11例，膀胱外翻7例，心外翻3例。超声检查未能识别出14例腹裂，误诊为脐膨出8例。未发现相关染色体异常，排除孕早期流产后，存活率为87%。超声检查未能识别出10例脐膨出，误诊为腹裂2例。40%的病例存在另一种结构异常，28%存在染色体异常。排除自然孕早期流产后，存活率为34%。尽管在远离地区儿科外科中心分娩时，腹裂或脐膨出患儿的伤口闭合平均延迟了2小时，但这并未对其预后产生不利影响。11例羊膜破裂序列胎儿中有1例存活。7例膀胱外翻婴儿中有6例存活，3例心外翻婴儿中有2例存活。
