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朗格汉斯细胞组织细胞增多症:可能与恶性生殖细胞肿瘤有关。

Langerhans' cell histiocytosis: possible association with malignant germ cell tumour.

作者信息

Ng W K, Lam K Y, Ng I O

机构信息

Department of Pathology, University of Hong Kong, Queen Mary Compound, Hong Kong.

出版信息

J Clin Pathol. 1995 Oct;48(10):963-5. doi: 10.1136/jcp.48.10.963.

DOI:10.1136/jcp.48.10.963
PMID:8537500
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC502957/
Abstract

A rare case of adult onset Langerhans' cell histiocytosis associated with dysgerminoma in a 35 year old Chinese woman is reported. The patient had a history of dysgerminoma of left ovary 15 years previously and had undergone surgery followed by radiotherapy and an uneventful recovery. She presented again in March 1994, this time with a left clavicular mass, which was shown histologically to be Langerhans' cell histiocytosis. The report illustrates the probable association between the two lesions, with some discussion on the underlying pathogenesis.

摘要

报告了一例35岁中国女性成人期朗格汉斯细胞组织细胞增多症合并无性细胞瘤的罕见病例。该患者15年前有左侧卵巢无性细胞瘤病史,接受了手术,随后进行了放疗,恢复顺利。1994年3月她再次就诊,此次出现左锁骨肿块,组织学检查显示为朗格汉斯细胞组织细胞增多症。该报告阐述了这两种病变之间可能的关联,并对潜在发病机制进行了一些讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/761b/502957/8a73d7987687/jclinpath00235-0082-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/761b/502957/beb80ac2ac57/jclinpath00235-0081-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/761b/502957/8a73d7987687/jclinpath00235-0082-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/761b/502957/beb80ac2ac57/jclinpath00235-0081-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/761b/502957/8a73d7987687/jclinpath00235-0082-a.jpg

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引用本文的文献

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Malignant histiocytosis associated with mediastinal germ cell tumor: A case report.恶性组织细胞增多症合并纵隔生殖细胞肿瘤:一例报告。
World J Clin Cases. 2022 Jul 16;10(20):7116-7123. doi: 10.12998/wjcc.v10.i20.7116. Epub 2022 May 16.
2
Langerhans cell histiocytosis (histiocytosis X).朗格汉斯细胞组织细胞增多症(组织细胞增多症X)。
Postgrad Med J. 1997 Jul;73(861):391-4. doi: 10.1136/pgmj.73.861.391.

本文引用的文献

1
Association of malignancy and Langerhans' cell histiocytosis: report of three cases.
Med Pediatr Oncol. 1993;21(6):451-3. doi: 10.1002/mpo.2950210612.
2
Association of Langerhans cell histiocytosis with malignant neoplasms.朗格汉斯细胞组织细胞增多症与恶性肿瘤的关联。
Cancer. 1993 Feb 1;71(3):865-73. doi: 10.1002/1097-0142(19930201)71:3<865::aid-cncr2820710334>3.0.co;2-0.
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Familial clustering of malignant germ cell tumors and Langerhans' histiocytosis.
Cancer. 1994 Apr 1;73(7):1980-3. doi: 10.1002/1097-0142(19940401)73:7<1980::aid-cncr2820730732>3.0.co;2-9.
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Langerhans' cell granulomatosis (histiocytosis X) associated with malignant lymphomas.朗格汉斯细胞组织细胞增生症(组织细胞增多症X)伴恶性淋巴瘤
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Hematologic malignancies associated with primary mediastinal germ-cell tumors.与原发性纵隔生殖细胞肿瘤相关的血液系统恶性肿瘤。
Ann Intern Med. 1985 May;102(5):603-9. doi: 10.7326/0003-4819-102-5-603.
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Leukemic differentiation of a mediastinal germ cell tumor.
Genes Chromosomes Cancer. 1989 Sep;1(1):83-7. doi: 10.1002/gcc.2870010113.
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Mediastinal germ cell tumors and histiocytosis.
Hum Pathol. 1988 May;19(5):586-90. doi: 10.1016/s0046-8177(88)80209-0.
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Hematologic neoplasia associated with primary mediastinal germ-cell tumors.与原发性纵隔生殖细胞肿瘤相关的血液系统肿瘤
N Engl J Med. 1990 May 17;322(20):1425-9. doi: 10.1056/NEJM199005173222004.