Shimonovitz S, Patz D, Ever-Hadani P, Singer L, Zacut D, Kidroni G, Ron M
Department of Obstetrics and Gynecology, Hadassah University Hospital Mount Scopus, Jerusalem, Israel.
J Perinat Med. 1995;23(4):279-82. doi: 10.1515/jpme.1995.23.4.279.
To evaluate the reliability of fluoride levels in the umbilical cord as reflecting neonate fluoride status.
Prospective study of fluoride levels of pregnant women at term and their neonates.
Delivery room and maternity unite of Hadassah Hospital Mount Scopus.
Fluoride serum levels were determined in the sera of 20 women with normal pregnancies at term, during delivery, in the corresponding mixed cord sera and neonatal sera at 24 hours after delivery.
The mean maternal fluoride serum level was 0.0303 microgram/ml (SD 9.015), mean cord fluoride serum level 0.0183 microgram/ml (SD 0.012), and mean neonatal fluoride serum 0.0380 microgram/ml (SD 0.016).
The significantly (p < 0.001) low mixed cord serum levels of fluoride as compared with neonatal and maternal serum levels may be explained by placental sequestration of fluoride. It is suggested that cord serum fluoride levels to not reflect fetal fluoride status.
评估脐带中氟含量作为反映新生儿氟状况的可靠性。
对足月孕妇及其新生儿的氟含量进行前瞻性研究。
哈达萨医院斯科普斯山院区产房和产科病房。
测定了20名足月正常妊娠妇女分娩时血清、相应混合脐带血清以及产后24小时新生儿血清中的氟含量。
母亲血清氟含量均值为0.0303微克/毫升（标准差9.015），脐带血清氟含量均值为0.0183微克/毫升（标准差0.012），新生儿血清氟含量均值为0.0380微克/毫升（标准差0.016）。
与新生儿和母亲血清水平相比，混合脐带血清中氟含量显著降低（p<0.001），这可能是由于胎盘对氟的隔离作用。提示脐带血清氟含量不能反映胎儿的氟状况。
