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[一名佩吉特病合并帕金森病患者的麻醉管理]

[Anesthetic management of a Paget's disease patient complicated with Parkinson disease].

作者信息

Tomioka T, Ogaki N, Asari H

机构信息

Second Department of Anesthesiology, Toho University School of Medicine, Tokyo.

出版信息

Masui. 1995 Oct;44(10):1384-7.

PMID:8538009
Abstract

Paget's disease is a metabolic disorder of unknown etiology characterized by excessively rapid remolding of bone. We report a case of Paget's disease complicated with Parkinson syndrome. A 69-year-old female patient was scheduled for ventriculo-peritoneostomy due to hydrocephalus. Her manifestations included disability to walk, slight deafness and muscular rigidity of limbs, without symptom of intracranial hypertension. After induction of anesthesia with thiopental and vecuronium, tracheal intubation with Macintosh laryngoscope was attempted but failed because mouth opening was restricted to only 3 cm. Again with Bullard laryngoscope, she was successfully intubated. During neurosurgical operation, the anesthesia was maintained with low concentration of isoflurane (under 0.3%), nitrous oxide and oxygen. The surgery was completed without adverse events such as disorder of autonomic nervous system. However 6-days after operation, ventilatory arrest occurred due to bronchial obstruction with sputum. Immediately, re-intubation was performed without any sequela and tracheostomy was also performed. In conclusion, as reported previously, intubation and postoperative pulmonary dysfunction should be carefully taken care of, and Bullard laryngoscope was useful for this patient.

摘要

佩吉特病是一种病因不明的代谢性疾病,其特征是骨骼重塑异常迅速。我们报告一例佩吉特病合并帕金森综合征的病例。一名69岁女性患者因脑积水计划行脑室-腹腔分流术。她的表现包括行走障碍、轻度耳聋和四肢肌肉僵硬,无颅内高压症状。在使用硫喷妥钠和维库溴铵诱导麻醉后,尝试用麦金托什喉镜进行气管插管,但因张口仅3厘米而失败。再次使用布拉德喉镜,成功为她进行了插管。在神经外科手术期间,麻醉维持采用低浓度异氟醚(低于0.3%)、氧化亚氮和氧气。手术顺利完成,未出现自主神经系统紊乱等不良事件。然而,术后第6天,因痰液阻塞支气管发生通气骤停。立即再次插管,未留下任何后遗症,同时也进行了气管切开术。总之,如先前报道,应谨慎处理插管和术后肺功能障碍问题,布拉德喉镜对该患者有用。

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