Ruiz-Lapuente M A, Armadans Gil L, Vaqué Rafart J, Rosselló Urgell J, Albertí Jaume J, Chacón Castro P
Servicio de Medicina Preventiva y Epidemiología, Ciutat Sanitària i Universitària Vall d'Hebron, Barcelona.
Med Clin (Barc). 1995 Nov 25;105(18):687-90.
Experimental studies have demonstrated that unfiltered coffee increases cholesterolemia. In Spain, filtered coffee is mainly consumed and its effect on cholesterolemia is controversial.
The relationship between coffee intake and the serum levels of total cholesterol was transversally studied in a population of 609 women between 18 to 65 years in age. The questionnaire and analyses were carried out in the context of periodic health examination.
The consumption of coffee was positively associated with cholesterolemia in subjects under 30 years of age (p < 0.01) and in the group from 30 to 45 years in age (p < 0.05). This association was found to be statistically significant on multivariant analysis (multiple lineal regression) after adjusting for age, body mass index, cholesterol consumed in the diet, smoking, alcohol consumption and physical activity.
Coffee was found to increase cholesterolemia in the female population and therefore a reduction in coffee intake would be recommendable in hypercholesterolemic subjects.
实验研究表明,未过滤的咖啡会升高胆固醇血症。在西班牙,人们主要饮用过滤咖啡,其对胆固醇血症的影响存在争议。
对609名年龄在18至65岁之间的女性进行横向研究,探讨咖啡摄入量与血清总胆固醇水平之间的关系。问卷调查和分析是在定期健康检查的背景下进行的。
在30岁以下的受试者(p < 0.01)和30至45岁的组中(p < 0.05),咖啡消费与胆固醇血症呈正相关。在调整年龄、体重指数、饮食中摄入的胆固醇、吸烟、饮酒和体育活动后,经多变量分析(多元线性回归)发现这种关联具有统计学意义。
发现咖啡会使女性人群的胆固醇血症升高,因此建议高胆固醇血症患者减少咖啡摄入量。