Sugimoto H, Takeda A, Masuyama J, Furuse M
Department of Radiology, Jichi Medical School, Japan.
Radiology. 1996 Jan;198(1):185-92. doi: 10.1148/radiology.198.1.8539375.
To investigate the role of magnetic resonance (MR) imaging in diagnosing early rheumatoid arthritis (RA).
Twenty patients (three men, 17 women; age range, 21-72 years) with clinically and radiologically proved RA underwent evaluation to define an MR imaging criterion for diagnosing synovial inflammation due to RA. Twenty-seven patients (16 with RA, 11 without RA [control patients]; three men, 24 women; age range, 19-75 years) suspected to have early RA but without radiographic abnormalities underwent evaluation to test the accuracy of using the criterion to diagnose RA. In each patient, coronal, fat-suppressed, and gadolinium contrast material-enhanced, T1-weighted images of both hands were obtained.
The MR imaging criterion was periarticular contrast material enhancement of the wrists or the metacarpophalangeal and/or proximal interphalangeal joints in both hands. In the diagnosis of early RA, sensitivity and negative predictive value were both 100%, specificity was 73%, and accuracy was 89%.
MR imaging is extremely useful in diagnosing early RA.
探讨磁共振成像（MR）在早期类风湿关节炎（RA）诊断中的作用。
对20例经临床及放射学证实为RA的患者（3例男性，17例女性；年龄范围21 - 72岁）进行评估，以确定诊断RA所致滑膜炎的MR成像标准。对27例疑似早期RA但无影像学异常的患者（16例RA患者，11例非RA患者[对照患者]；3例男性，24例女性；年龄范围19 - 75岁）进行评估，以检验该标准诊断RA的准确性。对每位患者均获取双手的冠状位、脂肪抑制、钆对比剂增强T1加权图像。
MR成像标准为双手腕关节或掌指关节和/或近端指间关节的关节周围对比剂增强。在早期RA的诊断中，敏感性和阴性预测值均为100%，特异性为73%，准确性为89%。
MR成像在早期RA的诊断中极其有用。
