Cysteinyl leukotrienes in asthma: current state of therapeutic evaluation.
作者信息
Taylor I K
机构信息
Department of Respiratory Medicine, Royal Infirmary Sunderland, Tyne and Wear, UK.
出版信息
Thorax. 1995 Sep;50(9):1005-10. doi: 10.1136/thx.50.9.1005.
Abstract
摘要
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Inhibition of platelet-activating factor-induced bronchoconstriction by the leukotriene D4 receptor antagonist ICI 204,219.白三烯D4受体拮抗剂ICI 204,219对血小板活化因子诱导的支气管收缩的抑制作用。
Am Rev Respir Dis. 1993 Jan;147(1):215-7. doi: 10.1164/ajrccm/147.1.215.
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Sulphidopeptide leukotrienes in asthma.
Clin Sci (Lond). 1993 May;84(5):501-10. doi: 10.1042/cs0840501.
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Potent leukotriene D4 receptor antagonist ICI 204,219 given by the inhaled route inhibits the early but not the late phase of allergen-induced bronchoconstriction.强效白三烯D4受体拮抗剂ICI 204,219经吸入途径给药可抑制变应原诱导的支气管收缩的早期阶段，但不能抑制晚期阶段。
Am Rev Respir Dis. 1993 Jun;147(6 Pt 1):1431-5. doi: 10.1164/ajrccm/147.6_Pt_1.1431.
5
Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses.口服白三烯抑制剂（MK-886）可阻断变应原诱导的气道反应。
Am Rev Respir Dis. 1993 Apr;147(4):839-44. doi: 10.1164/ajrccm/147.4.839.
6
The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma.齐留通抑制5-脂氧合酶对轻至中度哮喘的影响。
Ann Intern Med. 1993 Dec 1;119(11):1059-66. doi: 10.7326/0003-4819-119-11-199312010-00001.
7
The leukotriene-antagonist ICI-204,219 inhibits the early airway reaction to cumulative bronchial challenge with allergen in atopic asthmatics.
Eur Respir J. 1994 Feb;7(2):324-31. doi: 10.1183/09031936.94.07020324.
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Effects of 6 weeks of therapy with oral doses of ICI 204,219, a leukotriene D4 receptor antagonist, in subjects with bronchial asthma. ACCOLATE Asthma Trialists Group.口服白三烯D4受体拮抗剂ICI 204,219对支气管哮喘患者进行6周治疗的效果。ACCOLATE哮喘试验组。
Am J Respir Crit Care Med. 1994 Sep;150(3):618-23. doi: 10.1164/ajrccm.150.3.8087328.
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Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans.强效特异性口服血小板活化因子（PAF）受体拮抗剂UK,74505对人体气道及全身对吸入PAF反应的抑制作用。
Am J Respir Crit Care Med. 1994 Jul;150(1):35-40. doi: 10.1164/ajrccm.150.1.8025768.
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