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用灭活培养的抗狂犬病疫苗和抗狂犬病丙种球蛋白治疗被狂犬狼咬伤或疑似感染狂犬病者

[Treatment with inactivated cultured antirabies vaccine and antirabies gamma-globulin of persons biten by rabid wolves or those suspected of being rabid].

作者信息

Selimov M A, Kliueva E V, Aksenova T A, Lebedeva T A, Gribencha L F

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1978(12):105-12.

PMID:85398
Abstract

The authors present the results of using inactivated cultural rabies vaccine from the Vnukovo-32 strain in combination with rabies gamma-globulin for the treatment of 39 persons; of this number 28 were bitten by rabid wolves (the diagnosis was confirmed by laboratory methods), 25 had wounds of dangerous localization, and 3 were children from 7 to 15 years of age. In examining the sera of all the 39 bitten persons it was found that the scheme of combined vaccinations with inactivated cultural ribies vaccine and rabies gamma-globulin, officially acting in the USSR, in case of bites of dangerous localization led to formation of early continuous and lengthy passive and active immunity of adequate intensity.

摘要

作者介绍了使用源自Vnukovo - 32株的灭活培养狂犬病疫苗联合狂犬病丙种球蛋白治疗39人的结果;其中28人被狂犬咬伤(诊断经实验室方法确认),25人有危险部位的伤口,3人为7至15岁儿童。在检查所有39名被咬者的血清时发现,苏联官方采用的灭活培养狂犬病疫苗和狂犬病丙种球蛋白联合接种方案,在出现危险部位咬伤的情况下,可形成强度足够的早期持续且持久的被动和主动免疫。

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