Kondo K, Yokoyama Y, Yokoyama I, Kikuchi M, Akiyama S, Ito K, Takagi H
Department of Surgery II, Nagoya University School of Medicine, Japan.
Am J Gastroenterol. 1995 Dec;90(12):2213-5.
Two rare cases of early gastric carcinoma that followed gastrojejunostomy without gastrectomy are reported. The time intervals between the initial gastrojejunostomy and resection of the distal stomach with the formation of a gastrojejunal stoma were 30 yr and 33 yr, respectively. The Japanese classification confirmed both lesions as type IIc type mucosal early gastric cancer. In these two cases, with coexisting gastric ulcers, atrophic gastritis and diffuse intestinal metaplasia were observed in the lesions of the carcinomas. The potential correlation between the exposure of tissue to duodenal juice and the subsequent development of a gastric carcinoma is discussed. Literature regarding gastric carcinoma after gastrojejunostomy is reviewed.
本文报告了两例未行胃切除术而行胃空肠吻合术后发生早期胃癌的罕见病例。首次胃空肠吻合术与远端胃切除并形成胃空肠吻合口之间的时间间隔分别为30年和33年。日本分类法将这两个病变均确认为Ⅱc型黏膜早期胃癌。在这两例病例中,均伴有胃溃疡,在癌灶中观察到萎缩性胃炎和弥漫性肠化生。本文讨论了十二指肠液暴露与随后发生胃癌之间的潜在相关性。并对胃空肠吻合术后胃癌的相关文献进行了综述。