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[难治性癫痫女性的脑电图演变]

[Electroencephalographic evolution in women with refractory epilepsy].

作者信息

Azoubel A C, Silveira D C, Guerreiro C A

机构信息

Departamento de Neurologia, Faculdade de Ciências Médicas (FCM), Universidade Estadual de Campinas (UNICAMP), Brasil.

出版信息

Arq Neuropsiquiatr. 1995 Sep;53(3-A):384-9.

PMID:8540810
Abstract

We reviewed 444 EEGs of 62 women with medically refractory epilepsy, followed up for at least 5 years and that had 5 or more EEGs. According to our definitions we found 18 patients (29%) with frequent seizures, 16 (25.8%) with very frequent seizures, 16 (25.8%) with controlled seizures and 12 (19.3%) with occasional seizures. Four patients (6.5%) always showed normal EEGs, 30 (48.4%) had normal and abnormal EEGs and 28 (45.2%) only abnormal EEGs. Among the patients who had only normal EEGs, two had all seizures controlled, one had occasional seizures and one had frequent seizures. Among the patients who had normal and abnormal EEGs, 10 had controlled seizures, 5 had occasional seizures, 9 had frequent seizures and 6 had very frequent seizures. In the group of patients with always abnormal EEGs, 4 had controlled seizures, 6 had occasional seizures, 8 had frequent seizures, and 10 had very frequent seizures. In relation to the last EEG, it was normal in 7 (43.7%) of 16 patients with controlled seizures, in 3 (25%) of 12 patients with occasional seizures and in 7 (38.9%) of 18 patients with frequent seizures, and in none of the patients with very frequent seizures. The patients who had only normal EEGs seem to have a better outcome than those with abnormal EEGs. We observed that the last EEG was normal in 43.7% of the patients with controlled seizures. These data may suggest a relative importance of the EEG considering the long-term prognosis regarding seizure control.

摘要

我们回顾了62名患有药物难治性癫痫的女性的444份脑电图,这些患者至少随访了5年,且脑电图记录次数不少于5次。根据我们的定义,我们发现18例患者(29%)发作频繁,16例(25.8%)发作非常频繁,16例(25.8%)发作得到控制,12例(19.3%)发作偶尔出现。4例患者(6.5%)脑电图始终正常,30例(48.4%)脑电图有正常也有异常,28例(45.2%)脑电图仅为异常。在脑电图仅为正常的患者中,2例所有发作均得到控制,1例发作偶尔出现,1例发作频繁。在脑电图有正常也有异常的患者中,10例发作得到控制,5例发作偶尔出现,9例发作频繁,6例发作非常频繁。在脑电图始终异常的患者组中,4例发作得到控制,6例发作偶尔出现,8例发作频繁,10例发作非常频繁。关于最后一次脑电图,16例发作得到控制的患者中有7例(43.7%)脑电图正常,12例发作偶尔出现的患者中有3例(25%)脑电图正常,18例发作频繁的患者中有7例(38.9%)脑电图正常,而发作非常频繁的患者中无一例脑电图正常。脑电图仅为正常的患者似乎比脑电图异常的患者预后更好。我们观察到,发作得到控制的患者中43.7%的最后一次脑电图正常。这些数据可能表明,考虑到癫痫发作控制的长期预后,脑电图具有相对重要性。

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