Hirao I, Ellington A D
Department of Chemistry, Indiana University, Bloomington 47405, USA.
Curr Biol. 1995 Sep 1;5(9):1017-22. doi: 10.1016/s0960-9822(95)00205-3.
Results from in vitro selection experiments can be used to construct and test models for the evolution of the RNA world. Surprisingly, the success of selected RNAs at binding ligands and catalyzing reactions may make it difficult to determine precisely the lineage of molecular fossils, molecules that are believed to have survived from the RNA world to the present.
体外筛选实验的结果可用于构建和测试RNA世界进化的模型。令人惊讶的是,所选RNA在结合配体和催化反应方面的成功可能会使精确确定分子化石(即被认为从RNA世界存活至今的分子)的谱系变得困难。