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意大利威尼托大区临床化学外部质量评估计划的组织与结果

Organization and results of the Veneto region (Italy) external quality assessment program for clinical chemistry.

作者信息

Burlina A, Pradella M, Baldo F

机构信息

Istituto di Medicina di Laboratorio, Università degli Studi, Padova, Italy.

出版信息

Ann Ist Super Sanita. 1995;31(1):163-73.

PMID:8546366
Abstract

The Veneto region EQA program has been developed on the basis of the law that created the national health service and then on the regional social-health plans. Organizer and reference laboratory is the Biomedical Research Center in Castelfranco Veneto (TV). The aim of the program is to describe the state of the art in the public and private laboratories, and to evaluate the performances of each laboratory according to the schemes recommended by the European Committee for Clinical Laboratory Standards (ECCLS). Even though the program was not obligatory, participation has always been about 80% for public laboratories and increased from 70% to almost 100% in the private ones. The results showed very good interlaboratory agreement for electrolytes; iron assay has improved in the last two years; there have been standardization problems for urea and creatinine; among enzymes, the results are good for GGT and ALT, but not satisfactory for AST and more so for ALP. Since 1990, accuracy evaluation for 9 constituents has been introduced. The results are good for electrolytes and organic constituents but standardization problems are shown for enzyme methods, especially with ALP and AST.

摘要

威尼托大区的室间质量评价计划是依据创建国家医疗服务体系的法律以及随后的地区社会医疗计划制定的。组织者和参考实验室是位于威尼托大区卡斯泰尔弗朗科的生物医学研究中心。该计划的目的是描述公立和私立实验室的技术现状,并根据欧洲临床实验室标准委员会(ECCLS)推荐的方案评估每个实验室的性能。尽管该计划并非强制性的,但公立实验室的参与率一直约为80%,私立实验室的参与率则从70%增至近100%。结果显示,电解质的实验室间一致性非常好;铁测定在过去两年有所改善;尿素和肌酐存在标准化问题;在酶类检测中γ-谷氨酰转移酶(GGT)和丙氨酸氨基转移酶(ALT)的结果良好,但天冬氨酸氨基转移酶(AST)的结果不尽人意,碱性磷酸酶(ALP)的结果更是如此。自1990年以来,已引入对9种成分的准确性评估。电解质和有机成分的结果良好,但酶法存在标准化问题尤其是碱性磷酸酶和天冬氨酸氨基转移酶。

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