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Simian immunodeficiency virus DNA vaccine trial in macaques.

作者信息

Robinson H L, Lu S, Mustafa F, Johnson E, Santoro J C, Arthos J, Winsink J, Mullins J I, Montefiori D, Yasutomi Y

机构信息

Department of Pathology, University of Massachusetts Medical Center, Worcester 01655, USA.

出版信息

Ann N Y Acad Sci. 1995 Nov 27;772:209-11. doi: 10.1111/j.1749-6632.1995.tb44746.x.

DOI:10.1111/j.1749-6632.1995.tb44746.x
PMID:8546394
Abstract
摘要

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Simian immunodeficiency virus DNA vaccine trial in macaques.
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Enhancement of gp120-specific immune responses by genetic vaccination with the human immunodeficiency virus type 1 envelope gene fused to the gene coding for soluble CTLA4.通过基因疫苗接种增强针对gp120的免疫反应，该基因疫苗采用与编码可溶性CTLA4的基因融合的1型人类免疫缺陷病毒包膜基因。
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