Corbett T J, Saw H, Popat U, MacMahon E, Cohen B J, Knowles W A, Beard S, Prentice H G
Department of Haematology, Royal Free Hospital School of Medicine, London, UK.
Bone Marrow Transplant. 1995 Nov;16(5):711-3.
Chronic parvovirus B19 infection in the immunocompromised host may cause severe anaemia secondary to failure of erythropoiesis. This has been previously documented in patients with the Acquired Immune Deficiency Syndrome (AIDS), congenital immunodeficiencies and in children with acute lymphoblastic leukaemia during maintenance chemotherapy. We describe persistent parvovirus infection in a 14-year-old boy after HLA-matched sibling allogeneic bone marrow transplantation for acute lymphoblastic leukaemia in second remission.
免疫功能低下宿主中的慢性细小病毒B19感染可能因红细胞生成障碍而导致严重贫血。这在获得性免疫缺陷综合征（AIDS）患者、先天性免疫缺陷患者以及急性淋巴细胞白血病患儿维持化疗期间已有记载。我们描述了一名14岁男孩在第二次缓解期因急性淋巴细胞白血病接受人类白细胞抗原（HLA）匹配的同胞异基因骨髓移植后发生的持续性细小病毒感染。
