Pickford M A, Soutar D S
West of Scotland Regional Plastic and Oral Surgery Unit, Canniesburn Hospital, Glasgow, UK.
Br J Plast Surg. 1995 Dec;48(8):559-63. doi: 10.1016/0007-1226(95)90044-6.
A retrospective review of clinical records at Canniesburn Hospital has identified 6 patients in whom intraoral squamous carcinomas were excised and reconstruction performed by free tissue transfer on two separate occasions. The interval between procedures ranged from 8 months to 8 years. One dorsalis pedis flap was used and the other tissue transfers were radial forearm free flaps, two of which were osteocutaneous. One flap completely failed and the rest survived. There was no evidence of greater risk in carrying out a second microsurgical intraoral reconstruction in this series. 4 out of 6 patients remain alive following their second procedure, one after 9 years. The results suggest that in selected cases it may be worthwhile to carry out a major intraoral reconstruction on more than one occasion.
对坎尼伯恩医院临床记录的回顾性研究发现，有6例患者接受了口腔内鳞状细胞癌切除手术，并在两个不同时间通过游离组织移植进行了重建。两次手术之间的间隔时间为8个月至8年。其中1例使用了足背皮瓣，其他组织移植均为桡侧前臂游离皮瓣，其中2例为骨皮瓣。1例皮瓣完全坏死，其余均存活。在该系列研究中，没有证据表明进行第二次口腔显微重建手术存在更大风险。6例患者中有4例在第二次手术后存活，其中1例已存活9年。结果表明，在某些特定病例中，进行不止一次的大型口腔重建手术可能是值得的。
