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印度北部补体C4、B因子和C3多态性

Complement C4, factor B and C3 polymorphism in north India.

作者信息

Kramer J, Srivastava L M, Ferenczy E, Füst G

机构信息

National Institute of Haematology, Blood Transfusion and Immunology, Budapest, Hungary.

出版信息

Acta Microbiol Immunol Hung. 1995;42(3):315-9.

PMID:8548205
Abstract

Allotype frequencies of complement C4, factor B and C3 proteins were determined in 192 healthy unrelated individuals from North India. The gene frequencies for the most common factor B and C3 alleles were close to the data already published. As expected, significant differences were observed in this first study of C4 allotype frequencies among the North Indian population in comparison to European Caucasians. According to historians, Hungarian Gypsies migrated from India. In this study we demonstrate that our data for some complement allele frequencies are in accordance with the opinion of historians.

摘要

在来自印度北部的192名健康无关个体中测定了补体C4、因子B和C3蛋白的同种异型频率。最常见的因子B和C3等位基因的基因频率与已发表的数据接近。正如预期的那样,在对印度北部人群C4同种异型频率的首次研究中,与欧洲白种人相比观察到了显著差异。据历史学家称,匈牙利吉普赛人从印度迁徙而来。在这项研究中,我们证明了我们关于某些补体等位基因频率的数据与历史学家的观点一致。

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