CD28刺激的T细胞活化的药理学抑制作用。 - Suppr

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超能文献

Pharmacological inhibition of CD28-stimulated T cell activation.

作者信息

Wancio D, Damle N K, Bansbach C C

机构信息

Wyeth-Ayerst Research, Princeton, NJ 08543-8000, USA.

出版信息

Inflamm Res. 1995 Aug;44 Suppl 2:S203-4. doi: 10.1007/BF01778334.

DOI:10.1007/BF01778334

PMID:8548400

Abstract

摘要

相似文献

Pharmacological inhibition of CD28-stimulated T cell activation.CD28刺激的T细胞活化的药理学抑制作用。

Inflamm Res. 1995 Aug;44 Suppl 2:S203-4. doi: 10.1007/BF01778334.

Anti-CD28 antibody- and IL-4-induced human T cell proliferation is sensitive to rapamycin.抗CD28抗体和白细胞介素-4诱导的人T细胞增殖对雷帕霉素敏感。

Clin Exp Immunol. 1993 Nov;94(2):371-6. doi: 10.1111/j.1365-2249.1993.tb03459.x.

Evidence that FK506 and rapamycin block T cell activation at different sites relative to early reversible phosphorylation involving the protein phosphatases PP1 and PP2A.有证据表明，FK506和雷帕霉素在相对于涉及蛋白磷酸酶PP1和PP2A的早期可逆磷酸化的不同位点阻断T细胞活化。

Transplantation. 1991 Jun;51(6):1318-20. doi: 10.1097/00007890-199106000-00039.

Rapamycin: in vitro profile of a new immunosuppressive macrolide.雷帕霉素：一种新型免疫抑制大环内酯类药物的体外特性

Ann N Y Acad Sci. 1993 Jun 23;685:58-67. doi: 10.1111/j.1749-6632.1993.tb35852.x.

Comparison of effects of sirolimus on cytokine dependent and cytokine independent proliferation.

Inflamm Res. 1995 Aug;44 Suppl 2:S189-90. doi: 10.1007/BF01778325.

Assessment of mechanisms of action of immunosuppressive drugs using novel whole blood assays.

Transplant Proc. 2001 May;33(3):2119-20. doi: 10.1016/s0041-1345(01)01967-4.

FK 506 and rapamycin: molecular probes of T-lymphocyte activation.FK506与雷帕霉素：T淋巴细胞活化的分子探针

Transplant Proc. 1991 Dec;23(6):2850-5.

Rapamycin.雷帕霉素

Clin Exp Rheumatol. 1993 Mar-Apr;11 Suppl 8:S129.

Evaluation of the influence of FK 506, rapamycin, and cyclosporine on processing and presentation of particulate antigen by macrophages: assessment of a drug "carry-over" effect.评估FK 506、雷帕霉素和环孢素对巨噬细胞处理和呈递颗粒性抗原的影响：对药物“残留”效应的评估。

Transplant Proc. 1991 Dec;23(6):2957-8.

CD28 co-stimulatory signals induce IL-2 receptor expression on antigen-stimulated virgin T cells by an IL-2-independent mechanism.CD28共刺激信号通过一种不依赖白细胞介素-2的机制诱导抗原刺激的初始T细胞上白细胞介素-2受体的表达。

Int Immunol. 1996 Feb;8(2):159-69. doi: 10.1093/intimm/8.2.159.

本文引用的文献

Effects of rolipram and CI-930 on IL-2 mRNA transcription in human Jurkat cells.咯利普兰和CI-930对人Jurkat细胞中白细胞介素-2信使核糖核酸转录的影响。

Agents Actions. 1993;39 Spec No:C89-92. doi: 10.1007/BF01972730.

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif.T细胞抗原CD28通过一个胞质酪氨酸磷酸化-甲硫氨酸-任意氨基酸-甲硫氨酸基序与脂质激酶磷脂酰肌醇3激酶相互作用。

Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2834-8. doi: 10.1073/pnas.91.7.2834.

T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1.T细胞抗原CD28通过与激活抗原B7/BB-1相互作用介导与B细胞的黏附。

Proc Natl Acad Sci U S A. 1990 Jul;87(13):5031-5. doi: 10.1073/pnas.87.13.5031.

Increased cyclic adenosine monophosphate levels block progression but not initiation of human T cell proliferation.环磷酸腺苷水平升高会阻断人类T细胞增殖的进程，但不会阻止其启动。

J Immunol. 1990 Jul 15;145(2):449-55.

Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin.相关大环内酯类药物FK-506和雷帕霉素对小鼠T细胞活化的不同抑制机制。

J Immunol. 1990 Jan 1;144(1):251-8.

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones.CD28介导的信号传导共同刺激小鼠T细胞，并防止T细胞克隆中无反应性的诱导。

Nature. 1992 Apr 16;356(6370):607-9. doi: 10.1038/356607a0.

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