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[门静脉高压症患者结肠静脉曲张反复出血。经颈静脉肝内门体分流术(TIPS)植入成功预防复发]

[Recurrent bleeding from colonic varices in portal hypertension. The successful prevention of recurrence by the implantation of a transjugular intrahepatic stent-shunt (TIPS)].

作者信息

Allgaier H P, Ochs A, Haag K, Hauenstein K H, Tittor W, Rössle M, Blum H E

机构信息

Abteilung Innere Medizin II, Medizinische Universitätsklinik, Freiburg.

出版信息

Dtsch Med Wochenschr. 1995 Dec 22;120(51-52):1773-6. doi: 10.1055/s-2008-1055541.

Abstract

HISTORY AND CLINICAL FINDINGS

Sclerotherapy was performed in a 52-year-old patient with alcoholic liver cirrhosis (Child-Pugh stage A) for recurrent bleeding from oesophageal varices. Half a year later he again was admitted to hospital because of recurrent passage of bloody stools. The cardiovascular status was stable; the liver was enlarged by 15 cm in the medioclavicular line.

INVESTIGATIONS

Endoscopy revealed several varices in the colon near the right flexure. One of the varices had an ulcer of 5 mm size. Duplex sonography revealed portal hypertension with cirrhosis of the liver and partial thrombosis of the main trunk of the portal vein without any sign of cavernous transformation.

TREATMENT AND COURSE

Because of the partial portal vein thrombosis it was decided to insert a transjugular intrahepatic portosystemic stent shunt. This obviated the thrombosis and lowered the portosystemic pressure gradient by 6.8%. With the shunt functioning well there were no further bleedings in the subsequent year.

CONCLUSION

The only slightly invasive TIPS implantation is an effective therapeutic procedure for bleeding from colon varices caused by portal hypertension.

摘要

病史及临床检查结果

对一名52岁酒精性肝硬化(Child-Pugh A级)患者进行硬化治疗,以治疗食管静脉曲张反复出血。半年后,他因反复排血便再次入院。心血管状况稳定;肝脏在锁骨中线处增大了15厘米。

检查

内镜检查发现右结肠曲附近结肠有多处静脉曲张。其中一个静脉曲张有一个5毫米大小的溃疡。双功超声检查显示门静脉高压伴肝硬化,门静脉主干部分血栓形成,无海绵样变迹象。

治疗及过程

由于门静脉部分血栓形成,决定植入经颈静脉肝内门体分流支架。这消除了血栓形成,并使门体压力梯度降低了6.8%。分流功能良好,随后一年未再出血。

结论

唯一具有轻微侵入性的经颈静脉肝内门体分流术植入术是治疗门静脉高压引起的结肠静脉曲张出血的有效治疗方法。

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