Mulder C J, den Hartog G, Robijn R J, Thies J E
Department of Hepatogastroenterology, Rijnstate Hospital, Arnhem, The Netherlands.
Endoscopy. 1995 Aug;27(6):438-42. doi: 10.1055/s-2007-1005737.
In the past, a number of treatment modalities have been used for the management of a Zenker's diverticulum. These include transcervical diverticulectomy, myotomy, or laser or diathermy treatment via rigid endoscopes. Up to the present, no reports of the treatment of a Zenker's diverticulum with a flexible endoscope have been published.
In this study, we present the results of our first 20 patients (13 male; mean age 82 years) prospectively treated with a flexible endoscope applied through diathermy. All patients had significant symptoms such as dysphagia, recurrent aspiration pneumonia and/or weight loss.
Treatment using a mean of three sessions per patient was successful, with a good symptomatic response in all subjects. There were no severe complications associated with the therapy. Four patients complained about a sore throat for a few days. During follow-up (mean 6-7 months), three patients died due to unrelated causes, and 17 remained asymptomatic.
An important advantage is that it is possible to perform the treatment without general anesthesia, and therefore also in patients whose general health is poor. The technique can easily be performed in an interventional endoscopy unit. Our first experiences show that flexible endoscopic treatment is an effective and relatively safe method.
过去,已采用多种治疗方式来处理Zenker憩室。这些方式包括经颈憩室切除术、肌切开术,或通过硬式内镜进行激光或透热疗法。截至目前,尚无关于使用软性内镜治疗Zenker憩室的报道。
在本研究中,我们展示了首批20例患者(13例男性;平均年龄82岁)的治疗结果,这些患者均接受了通过透热疗法应用软性内镜的前瞻性治疗。所有患者均有吞咽困难、反复吸入性肺炎和/或体重减轻等明显症状。
每位患者平均接受三次治疗,治疗成功,所有受试者的症状均有良好改善。治疗未出现严重并发症。4例患者抱怨咽痛持续了几天。在随访期间(平均6 - 7个月),3例患者因无关原因死亡,17例患者仍无症状。
一个重要优点是无需全身麻醉即可进行治疗,因此对于全身状况较差的患者也适用。该技术可在介入内镜科室轻松实施。我们的初步经验表明,软性内镜治疗是一种有效且相对安全的方法。