卤泛群治疗恶性疟
Halofantrine in the treatment of falciparum malaria.
作者信息
Patel K H, Shastri H, Patel R Z, Parikh P J, Patel H R, Pathak K J
机构信息
Department of Medicine, Pathology, Medical College, Baroda, India.
出版信息
Indian J Malariol. 1995 Mar;32(1):1-5.
50 patients (45 males + 5 females) suffering from acute uncomplicated attack of Plasmodium falciparum (Pf) malaria were treated with 1500 mg of halofantrine divided in three doses of 500 mg each given at an interval of 6 h. Results showed there were no primary treatment failures. Average Parasite Clearance Time (av. PCT) was 51.12 h and average Fever Clearance Time (av. FCT) was 31.25 h. Adverse Drug Reactions (ADR) were mild and self limiting. We conclude that halofantrine is a quite safe and effective new antimalarial agent in the treatment of Pf malaria cases.
50例急性非复杂性恶性疟原虫（Pf）疟疾发作患者（45例男性+5例女性）接受了1500毫克卤泛群治疗，分三次给药，每次500毫克，间隔6小时。结果显示无原发性治疗失败情况。平均寄生虫清除时间（av. PCT）为51.12小时，平均退热时间（av. FCT）为31.25小时。药物不良反应（ADR）轻微且为自限性。我们得出结论，卤泛群是一种治疗Pf疟疾病例相当安全有效的新型抗疟药。
Zotero 插件