Diallinas G, Gorfinkiel L, Arst H N, Cecchetto G, Scazzocchio C
Institut de Génétique et Microbiologie, Université de Paris-Sud, Centre d'Orsay, France.
Folia Microbiol (Praha). 1994;39(6):513-4. doi: 10.1007/BF02814078.
The ascomycete fungus Aspergillus nidulans can utilize purines (adenine, guanine, hypoxanthine, xanthine, and uric acid) as sole nitrogen sources [1]. The expression of most structural genes involved in the pathway of purine uptake and catabolism is subject to uric acid induction, mediated by the product of the positive regulatory gene uaY, and to nitrogen metabolite repression, mediated by the product of the general, positive-acting, GATA-like transcription factor, encoded by the areA gene [1].
子囊菌构巢曲霉能够利用嘌呤（腺嘌呤、鸟嘌呤、次黄嘌呤、黄嘌呤和尿酸）作为唯一氮源[1]。参与嘌呤摄取和分解代谢途径的大多数结构基因的表达受尿酸诱导（由正向调节基因uaY的产物介导）以及氮代谢物阻遏（由普遍的、正向作用的、GATA样转录因子的产物介导，该转录因子由areA基因编码）的调控[1]。
