身高与髋部骨折：一项对90000名女性的队列研究。
Body height and hip fracture: a cohort study of 90,000 women.
作者信息
Hemenway D, Feskanich D, Colditz G A
机构信息
Department of Health Policy and Management, Harvard School of Public Health, Boston, MA 02115, USA.
出版信息
Int J Epidemiol. 1995 Aug;24(4):783-6. doi: 10.1093/ije/24.4.783.
BACKGROUND
Hip fractures are a major public health problem. Recent studies have noted a connection between body height and hip fracture.
METHODS
We investigated the relationship between body height and hip fracture using a prospective cohort of over 92,000 American, predominantly white, female nurses who were followed for 10 years, from June 1980 to June 1990. The women, participants in the Nurses Health Study, were aged 35-59 in 1980.
RESULTS
Women 5'8" or taller were more than twice as likely as women under 5'2" to sustain a hip fracture, after accounting for age, body mass index, cigarette smoking and alcohol consumption (multivariate relative risk 2.40, 95% confidence interval: 1.43-4.02; P for trend < 0.0001).
CONCLUSION
Height appears to be an important independent risk factor for hip fracture among American women. Height should be included as a confounder in studies of hip fracture, and taller, elderly women should be advised to consider preventive measures.
背景
髋部骨折是一个重大的公共卫生问题。近期研究指出了身高与髋部骨折之间的联系。
方法
我们利用一个前瞻性队列研究了身高与髋部骨折之间的关系，该队列包含超过92000名美国护士，主要为白人女性，从1980年6月至1990年6月对她们进行了为期10年的随访。这些女性是护士健康研究的参与者，在1980年时年龄为35 - 59岁。
结果
在考虑年龄、体重指数、吸烟和饮酒因素后，身高5英尺8英寸及以上的女性发生髋部骨折的可能性是身高低于5英尺2英寸女性的两倍多（多变量相对风险2.40，95%置信区间：1.43 - 4.02；趋势P值<0.0001）。
结论
身高似乎是美国女性髋部骨折的一个重要独立风险因素。在髋部骨折研究中应将身高作为一个混杂因素纳入考虑，对于身材较高的老年女性，应建议她们考虑采取预防措施。
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