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保加利亚一项牛奶氟化项目对龋齿的预防效果。

Dental caries-reducing effects of a milk fluoridation project in Bulgaria.

作者信息

Pakhomov G N, Ivanova K, Moller I J, Vrabcheva M

机构信息

World Health Organization, Oral Health Unit, Geneva, Switzerland.

出版信息

J Public Health Dent. 1995 Fall;55(4):234-7. doi: 10.1111/j.1752-7325.1995.tb02375.x.

Abstract

OBJECTIVES

The aim of the present study was to investigate the effects of a community-based milk fluoridation project on dental caries.

METHODS

Fluoridated milk was provided to about one-half of kindergarten and other schoolchildren in Asenovgrad, a town in the southern part of Bulgaria. The estimated daily milk consumption was 200 ml containing 1 mg of fluoride (approximately 5 ppm F). Cross-sectional samples of 6 1/2-year-olds in Asenovgrad and Panaguriche (a nearby town selected as the reference community) were examined at the start of the study in 1988 and after three years. Additional cross-sectional samples of 7 1/2-year-olds in Asenovgrad who were and were not drinking fluoridated milk were examined at baseline and at three years to provided an internal control group. Samples of 6 1/2 and 8 1/2-year-olds from Asenovgrad and Karlovo were examined in 1993 to provide for five-year follow-up comparisons.

RESULTS

In 6 1/2-year-old children who had consumed fluoridated milk for three years, there was a decrease in the mean dmft per child of 40 percent and in the mean DMFT of 89 percent compared to children examined at baseline. Children in Asenovgrad who were 4 1/2 years old at the start of the study and had been drinking fluoridated milk for three years had on average 44 percent fewer dmft and 83 percent fewer DMFT at 7 1/2 years of age than those not drinking fluoridated milk. After five years the dmft index was 40 percent less and the DMFT index 79 percent less in those children who had participated in the full five years of the program compared to the control group.

CONCLUSIONS

Results seem to confirm the caries-reducing effects of milk fluoridation found in previous studies. Unexpected large caries reductions obtained in this nonexperimental study, however, probably cannot be attributed to the fluoridation of milk alone. The mere introduction of the project might have led to other changes affecting dental caries, such as improved oral hygiene and better dietary habits.

摘要

目的

本研究旨在调查一项基于社区的牛奶氟化项目对龋齿的影响。

方法

向保加利亚南部城镇阿森诺夫格勒约一半的幼儿园儿童和其他学童提供氟化牛奶。估计每日牛奶摄入量为200毫升,含1毫克氟化物(约5 ppm F)。1988年研究开始时及三年后,对阿森诺夫格勒和帕纳古里什泰(附近一个被选为对照社区的城镇)6.5岁儿童的横断面样本进行了检查。在基线期和三年时,对阿森诺夫格勒7.5岁饮用和未饮用氟化牛奶的儿童进行了额外的横断面样本检查,以提供一个内部对照组。1993年对阿森诺夫格勒和卡尔洛沃6.5岁和8.5岁儿童的样本进行了检查,以进行五年随访比较。

结果

与基线期检查的儿童相比,饮用氟化牛奶三年的6.5岁儿童,每名儿童的平均乳牙龋失补牙数(dmft)减少了40%,恒牙龋失补牙数(DMFT)减少了89%。在研究开始时为4.5岁且饮用氟化牛奶三年的阿森诺夫格勒儿童,7.5岁时的平均dmft比未饮用氟化牛奶的儿童少44%,DMFT少83%。与对照组相比,参与该项目满五年的儿童在五年后dmft指数降低了40%,DMFT指数降低了79%。

结论

结果似乎证实了先前研究中发现的牛奶氟化对减少龋齿的作用。然而,在这项非实验性研究中获得的意外大幅龋齿减少,可能不能仅归因于牛奶的氟化。该项目的单纯实施可能导致了其他影响龋齿的变化,如口腔卫生改善和饮食习惯更好。

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