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白纹伊蚊、埃及伊蚊和致倦库蚊(双翅目:蚊科)对辛德毕斯病毒的实验室传播

Laboratory transmission of Sindbis virus by Aedes albopictus, Ae. aegypti, and Culex pipiens (Diptera: Culicidae).

作者信息

Dohm D J, Logan T M, Barth J F, Turell M J

机构信息

Department of Epidemiology, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702-5011, USA.

出版信息

J Med Entomol. 1995 Nov;32(6):818-21. doi: 10.1093/jmedent/32.6.818.

Abstract

The susceptibility of Aedes albopictus (Skuse) for Sindbis (SIN) virus was examined in the laboratory. Ae. albopictus, Ae. aegypti (L.), and Culex pipiens (L.) became infected with and subsequently transmitted SIN virus by bite to chicks after feeding on viremic 1-d-old chicks. After ingesting 10(5.3) plaque-forming units (PFU)/ml, Ae. albopictus had the highest transmission rate (30%) of the 3 species. Transmission by Ae. aegypti was less efficient (7%), whereas none of the Cx. pipiens transmitted virus. Transmission rates were higher for Ae. albopictus (53%) and Cx. pipiens (37%) when they fed on chicks with a viremia of 10(8.4) PFU/ml. Ae. aegypti was not tested at this dose. Based on these studies, the increased geographic distribution of Ae. albopictus, and its opportunistic feeding behavior, this species should be considered as a potential bridge vector of SIN virus.

摘要

在实验室中检测了白纹伊蚊(Skuse)对辛德毕斯(SIN)病毒的易感性。白纹伊蚊、埃及伊蚊(L.)和致倦库蚊(L.)在吸食感染病毒1日龄雏鸡的血液后,通过叮咬感染并随后将SIN病毒传播给雏鸡。在摄入10(5.3) 空斑形成单位(PFU)/毫升后,白纹伊蚊在这3个物种中的传播率最高(30%)。埃及伊蚊的传播效率较低(7%),而致倦库蚊均未传播病毒。当白纹伊蚊和致倦库蚊吸食病毒血症为10(8.4) PFU/毫升的雏鸡血液时,它们的传播率更高,分别为53%和37%。该剂量下未对埃及伊蚊进行检测。基于这些研究,考虑到白纹伊蚊地理分布的增加及其机会性摄食行为,该物种应被视为SIN病毒的潜在桥梁媒介。

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