[266例患者的经直肠超声引导下活检]
[Transrectal ultrasound guided biopsies in 266 patients].
作者信息
Kurita Y, Kageyama S, Ushiyama T, Suzuki K, Fujita K, Kawabe K
机构信息
Department of Urology, Hamamatsu University School of Medicine.
出版信息
Nihon Hinyokika Gakkai Zasshi. 1995 Nov;86(11):1631-5. doi: 10.5980/jpnjurol1989.86.1631.
BACKGROUND
The objective of this study is to evaluate the diagnostic utility of digital rectal examination (DRE), prostate specific antigen (PSA) and transrectal ultrasonography (TRUS) for prostate cancer.
METHODS
On 266 patients ultrasonography guided transrectal biopsies were performed using the automatic biopsy gun fitted with an 18 gauge biopsy needle.
RESULTS
There was no major complication. Cancers were found in 52 patients (19.5%), and 16 of them were not identified by echography. Among 67 hypoechoic areas detected by echography, 36 (53.7%) were found to be cancer. The positive predictive value of DRE was 52.1% and that of PSA and TRUS were 24.4% and 53.7%, especially the rate increased to 93.7% by combining of these three techniques.
CONCLUSION
These results suggest that the use of DRE, PSA in conjunction with TRUS enhances early detection of prostate cancer.
背景
本研究的目的是评估直肠指检（DRE）、前列腺特异性抗原（PSA）和经直肠超声检查（TRUS）对前列腺癌的诊断效用。
方法
对266例患者使用配备18号活检针的自动活检枪进行超声引导下经直肠活检。
结果
未发生重大并发症。52例患者（19.5%）发现患有癌症，其中16例未通过超声检查发现。在超声检查发现的67个低回声区域中，36个（53.7%）被发现为癌症。直肠指检的阳性预测值为52.1%，PSA和TRUS的阳性预测值分别为24.4%和53.7%，尤其是这三种技术联合使用时，该比率增至93.7%。
结论
这些结果表明，联合使用直肠指检、PSA和TRUS可提高前列腺癌的早期检测率。
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