鞘内注射巴氯芬治疗运动障碍。

Intrathecal baclofen for motor disorders.

作者信息

Penn R D, Gianino J M, York M M

机构信息

Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60612, USA.

出版信息

Mov Disord. 1995 Sep;10(5):675-7. doi: 10.1002/mds.870100524.

DOI:10.1002/mds.870100524

PMID:8552124

Abstract

To test the efficacy of intrathecal baclofen in various movement disorders, 18 patients with dystonia, head trauma, cerebral palsy, rigidity, or painful spasms underwent a trial of intrathecal baclofen. Ten went on to permanent implantation with an infusion pump to provide long-term treatment. Patients with a component of spasticity, painful spasms, or focal dystonias did best, and no response was seen in patients with rigidity due to anoxic encephalopathy. A videotape of responses is provided.

摘要

为测试鞘内注射巴氯芬对各种运动障碍的疗效，18例患有肌张力障碍、头部创伤、脑瘫、僵硬或疼痛性痉挛的患者接受了鞘内注射巴氯芬试验。其中10例患者继续使用输液泵进行永久性植入以提供长期治疗。伴有痉挛、疼痛性痉挛或局灶性肌张力障碍的患者效果最佳，而因缺氧性脑病导致僵硬的患者未见反应。文中提供了反应的录像带。