Emmerson B T
University of Queensland, Department of Medicine, Princess Alexandra Hospital, Woolloongabba, Brisbane, Australia.
N Engl J Med. 1996 Feb 15;334(7):445-51. doi: 10.1056/NEJM199602153340707.
We now have sufficient knowledge to be able to identify the factors contributing to hyperuricemia in most patients with gout. Some of these factors, such as obesity, a high-purine diet, regular alcohol consumption, and diuretic therapy, may be correctable. In patients with persistent hyperuricemia, regular medication should lower the serum urate concentration to an optimal level. The continuing challenge is to educate patients about correctable factors and the importance of regular medication and ensure their compliance so that attacks of gout do not recur.
我们现在有足够的知识来识别大多数痛风患者高尿酸血症的促成因素。其中一些因素，如肥胖、高嘌呤饮食、经常饮酒和利尿治疗，可能是可以纠正的。对于持续性高尿酸血症患者，规律用药应将血清尿酸浓度降至最佳水平。持续存在的挑战是教育患者了解可纠正因素以及规律用药的重要性，并确保他们遵医嘱，从而使痛风发作不再复发。
