Checchini M, Magni M, Scaglione M, Vaccarella A
Unità Operativa di Cardiologia, INRCA, Casatenovo, Como.
Minerva Cardioangiol. 1995 Sep;43(9):379-81.
The authors describe the case of an epileptic patient in chronic therapy with carbamazepine, and with plasma concentration of the drug in therapeutical range, who suffers from persistent sinus tachycardia. At the present time the observations available in the literature on cardiac toxicity of carbamazepina concern the appearance of sinus tachycardia as consequence of overdose and of blocks of conduction in elderly with carbamazepine in therapeutical range.
作者描述了一名长期接受卡马西平治疗且药物血浆浓度处于治疗范围内的癫痫患者,该患者患有持续性窦性心动过速。目前,文献中关于卡马西平心脏毒性的观察结果涉及因用药过量导致的窦性心动过速以及治疗范围内使用卡马西平的老年人出现传导阻滞的情况。