甲状腺髓样癌转移至乳腺。
Medullary carcinoma of the thyroid metastatic to breast.
作者信息
Kiely N, Williams N, Wilson G, Williams R J
机构信息
Department of Surgery, North Manchester General Hospital, Crumpsall, UK.
出版信息
Postgrad Med J. 1995 Dec;71(842):744-5. doi: 10.1136/pgmj.71.842.744.
Medullary carcinoma of the thyroid commonly spreads to the lymphatics and later on in the disease process, to distant sites such as lung, liver and bone. Spread to the breast is rare (only two previous reported cases) and presents a major diagnostic dilemma. We report a case of metastatic medullary carcinoma of the thyroid which presented as a primary breast nodule with ipsilateral axillary lymphadenopathy. Clearly it was important to distinguish this tumour from a breast primary as each are managed differently. Both cytological and radiological investigations were inconclusive but excision biopsy was diagnostic.
甲状腺髓样癌通常会扩散至淋巴管，在疾病进展后期还会扩散至肺、肝和骨等远处部位。扩散至乳腺的情况较为罕见（此前仅报告过两例），这会带来重大的诊断难题。我们报告了一例甲状腺转移性髓样癌，该病例表现为原发性乳腺结节并伴有同侧腋窝淋巴结病。显然，将这种肿瘤与原发性乳腺癌区分开来很重要，因为二者的治疗方式不同。细胞学和放射学检查均无定论，但切除活检具有诊断意义。
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